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Magnesium Supplementation Helpful in Type II Diabetes – Diabetes Care

Question:

Quentin, Thanks for this link!!!  It’s fantastic! http://www.nal.usda.gov/fnic/foodcomp/Data/SR15/wtrank/wt_rank.html Wow, Black beans are good for everything, and they are one of my favorite foods.  Cool.  :-) Linda

Response:

> http://www.nal.usda.gov/fnic/foodcomp/Data/SR15/wtrank/wt_rank.html > Don’t be tempted to hit print unless you want a 28 page list including > pages and pages of food items with hardly any magnesium.  The better > option is to use the Print Current Page option in Windows.

Thanks, Quentin.  No Windows here, but most operating systems have a similar single-page feature. That link (and "neighboring" links) ought to be quite useful!

Response:

This post not CC’d by email > http://www.nal.usda.gov/fnic/foodcomp/Data/SR15/wtrank/wt_rank.html > Don’t be tempted to hit print unless you want a 28 page list including > pages and pages of food items with hardly any magnesium.  The better > option is to use the Print Current Page option in Windows. >Thanks, Quentin.  No Windows here, but most operating systems >have a similar single-page feature. >That link (and "neighboring" links) ought to be quite useful!

G’day G’day Wes,  You might like http://www.nal.usda.gov/fnic/foodcomp/srch/search.htm I know you’ll heed the warning on the length of time it takes to down 30 Megabytes.  One thing I found limiting is the direction of the search one has to start with a food.  I’d love to be able to start with any nutrient eg a specific amino acid.   Walford do some neat software that will allow some fancy searching starting with one or more nutrients. Unfortunately the it uses a reasonable but never the less restricted set of nutrients.   I have the entire SR15 database in Access.  Now I haven’t the foggiest of how to search it.  Darn … another learning curve looms. Does anyone know of a friendly front end? Best wishes, — Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "... and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

Jenny, thank you for posting this...I'm sorry that some saw fit to denegrate what might be helpful to those diabetics who need more magnesium in their diets.  I'm going to try it.  Hell, all it can do is make me better, right?  If it doesn't, no harm done. I'll be so glad when the docs get a definitive answer as to why we're diabetics besides the 'you eat too much' train of thought. Bonita - Hide quoted text -- Show quoted text - > Magnesium Supplement Helpful in Diabetes Control > By David Douglas > NEW YORK (Reuters Health) Apr 16 - Oral magnesium supplementation improves > insulin sensitivity and metabolic control in certain type 2 diabetics, > researchers report in the April issue of Diabetes Care.

Response:

Hey all, For those of you with migraines, magnesium helps migraines tremendously!  In fact, in Oregon, Medicaid added it to the list of things docs are supposed to prescribe for migraines. It helps me!!  :-) Linda

- Hide quoted text -- Show quoted text -> This post not CC'd by email >> The search engine makes it look like there's yet another great reason to eat >> sunflower seeds roasted in the shell. They've got lots of magnesium besides >> the healthy oils, fiber, AND the ability to make a person feel like they've >> eaten something when they haven't. >>>Just for the fun of it see if you can discover which categories of >>>food have the most magnesium per 100 gram. >>>http://yarrow.best.vwh.net/Usda_data/foods.cgi?state_num=5 >Note that it's per 100 grams, though.  How many "servings" >of each is 100 grams?  It may be that what looks like the >"best" is less so when you consider eating 100 grams of each. >It's also interesting to note that although the highest >concentrations are in this category, three other categories >each have _one_ item with high concentrations of magnesium. >My father was recently diagnosed diabetic.  He has little >experience at reading food labels (grew his own food much >of his life) so I wrote for him a "short" (four pages and >growing!) overview of nutrition.  One excerpt follows: >       Knowingly selecting certain foods (once you know what >       they are) can more reliably meet certain needs.  On the >       other hand, plenty of opportunists (and misguided fans) >       are constantly proclaiming this or that food item as >       the "miracle cure" for almost everything.  But faddishly >       consuming large amounts of one alleged "miracle food" is >       a good way to be deficient in something that food lacks. >       If you don't have time for extensive study, one approach >       is just to "hedge your bets" by having a wide variety of >       foods, especially vegetables of various colors. > G'day G'day Wes, >  You might like this nutrient list. > It takes an Acrobat reader to view. > If you select the W icon for magnesium you will get a .pdf for > magnesium containing foods sorted from highest to lowest content. > http://www.nal.usda.gov/fnic/foodcomp/Data/SR15/wtrank/wt_rank.html > Don't be tempted to hit print unless you want a 28 page list including > pages and pages of food items with hardly any magnesium.  The better > option is to use the Print Current Page option in Windows. > Best wishes, > -- > Quentin Grady       ^  ^  / > New Zealand,       >#,#< [ >                     / / > "... and the blind dog was leading." > http://homepages.paradise.net.nz/quentin

Response:

Just so you might add my experience along with others.  My doctor gave me 500mg twice a day for 2 weeks and now I am on 500mgs once a day. This has worked very well for me. Zbrigid - Hide quoted text -- Show quoted text -> What I like about the study (besides the fact that she managed to >publish in reputable, peer-reviewed journals) is the fact that she went >directly to HOMA (a measure of Insulin Resistance) and derived a conclusion >based on first principles. . .a direct reduction in Insulin Resistance.

Response:

This post not CC'd by email >Just so you might add my experience along with others.  My doctor gave >me 500mg twice a day for 2 weeks and now I am on 500mgs once a day. >This has worked very well for me. >Zbrigid

G'day G'day Brigid,   Did the doctor explain the rationale for putting you on magnesium?   Had you, for instance, had red blood count magnesium levels evaluated? Obviously you were pleased with results.  A couple of weeks is to short a time to have noticed a change in A1c so I am wondering what you observed that you were please with. Thanks, > > What I like about the study (besides the fact that she managed to > >publish in reputable, peer-reviewed journals) is the fact that she went > >directly to HOMA (a measure of Insulin Resistance) and derived a conclusion > >based on first principles. . .a direct reduction in Insulin Resistance.

-- Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "... and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

This post not CC'd by email - Hide quoted text -- Show quoted text -> The search engine makes it look like there's yet another great reason to eat > sunflower seeds roasted in the shell. They've got lots of magnesium besides > the healthy oils, fiber, AND the ability to make a person feel like they've > eaten something when they haven't. >>Just for the fun of it see if you can discover which categories of >>food have the most magnesium per 100 gram. >>http://yarrow.best.vwh.net/Usda_data/foods.cgi?state_num=5 >Note that it's per 100 grams, though.  How many "servings" >of each is 100 grams?  It may be that what looks like the >"best" is less so when you consider eating 100 grams of each. >It's also interesting to note that although the highest >concentrations are in this category, three other categories >each have _one_ item with high concentrations of magnesium. >My father was recently diagnosed diabetic.  He has little >experience at reading food labels (grew his own food much >of his life) so I wrote for him a "short" (four pages and >growing!) overview of nutrition.  One excerpt follows: >       Knowingly selecting certain foods (once you know what >       they are) can more reliably meet certain needs.  On the >       other hand, plenty of opportunists (and misguided fans) >       are constantly proclaiming this or that food item as >       the "miracle cure" for almost everything.  But faddishly >       consuming large amounts of one alleged "miracle food" is >       a good way to be deficient in something that food lacks. >       If you don't have time for extensive study, one approach >       is just to "hedge your bets" by having a wide variety of >       foods, especially vegetables of various colors.

G'day G'day Wes,  You might like this nutrient list. It takes an Acrobat reader to view. If you select the W icon for magnesium you will get a .pdf for magnesium containing foods sorted from highest to lowest content. http://www.nal.usda.gov/fnic/foodcomp/Data/SR15/wtrank/wt_rank.html Don't be tempted to hit print unless you want a 28 page list including pages and pages of food items with hardly any magnesium.  The better option is to use the Print Current Page option in Windows. Best wishes, -- Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "... and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

This post not CC'd by email > What I like about the study (besides the fact that she managed to >publish in reputable, peer-reviewed journals) is the fact that she went >directly to HOMA (a measure of Insulin Resistance) and derived a conclusion >based on first principles. . .a direct reduction in Insulin Resistance. >So many of these diabetic studies are based on fasting bG or HbA1c.   When >you look at them, they really state: >    " Some folks who were wildly out of control used our stuff,  and they >ended up a bit less out of control. . .so it must be wonderful"

G'day G'day Al,   I often wonder where they recruit participants.  Instead of asking them to participate in a study, I'd be more inclined to enrol them in a program to get their bg under control.  Then of course the research wouldn't get done and ...   >She said: >    "I measured magnesium levels and Insulin Resistance.    Magnesium levels >were low,  Insulin Resistance was high. >   I gave them magnesium.   Magnesium levels went up,  Insulin Resistance >went down a lot though it was still too high"

That about summarises it. >Good of you to put the time in and pick this thing apart for us. >Regards >  Old Al

-- Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "... and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

This post not CC'd by email - Hide quoted text -- Show quoted text ->If you don't like the idea of supplementation, here is a site I >found after a *very* quick Google for "Best food sources - >magnesium". >http://www.solidrecords.com/Net_Vibes/Food_Connection/Nutrition_Cent >er/Magnesium.html >It's probably as good as any other I'd find. >Almonds or hazelnuts --         2 ounces 170 mg >Spinach, fresh, cooked ---      1 cup    155 mg >Swiss chard, fresh, cooked ---  1 cup    150 mg >Sunflower seeds, dried ---     1/4 cup   130 mg >Halibut or mackerel, cooked --- 4 ounces 120 mg >Tofu ---                        4 ounces 120 mg >Wheat bran ---                1/4 ounces  90 mg >Rice, brown, cooked ---         1 cup     85 mg >Avocado ---                     6 ounces  70 mg >Beans (legumes), cooked ---     1 cup     35 mg >Adult RDA is 400 mg >Magnesium helps reduce the risk of heart disease. It also works with >calcium in forming bones and teeth. >Annette

G'day G'day Annette,  Thanks for the list. Here is one from an Australian source. It isn't intended as a better list.   What it does do is give us a chance to look at the pitfalls of lists. Almonds          1/2cup        200 mg Buckwheat        1/2cup        186 mg Cashew nuts      1/2cup        169 mg Wheat bran       1/2cup        168 mg Spinach boiled   1 cup         148 mg Soybeans, cooked 1 cup         141 mg Wheatgerm        1/2 cup       130 mg Peanuts          1/2 cup       124 mg Baked beans      1 cup         105 mg Beet greens      1 cup          92 mg Halibut baked    85 grams       87 mg Black-eyed peas  1 cup          82 mg Brown rice       1 cup          80 mg Kidney beans     1 cup          75 mg Chickpeas        1 cup          74 mg Artichokes       1              72 mg Green peas       1 cup          59 mg Apricots dried   1 cup          58 mg Oatmeal cooked   1 cup          53 mg Sweetcorn        1 cup          49 mg Raisins          1 cup          46 mg Wholewheat sphag 1 cup          40 mg Avocado          1/2            35 mg Pearl barley     1 cup          33 mg OK.  This one of the many lists I used to help me pick two of my dietary staples, almonds and buckwheat.   However there are reasons to be cautious with lists.   1. The amounts chosen are sometimes quite unsuitable for some personal reason eg 1 cup of raisins doesn't seem a rational choice for T2 diabetics, wheat bran seems like just the thing a celiac doesn't need. 2.  There is a seductive illusion that things not included on this list are low in magnesium ie less than 33 mg of Magnesium. I leave it as an exercise for anyone who doesn't take things at face value to find out the magnesium content of cocoa or snake beans. 3.  Since the RDA is about 300 mg it is tempting to think, "Oh what the heck, I'll take a supplement."   Well there is a caution that comes free with the list "Magnesium supplements should not be taken by those with impaired kidney function or serious heart disease."   Looked at more rationally if one obtains half the magnesium RDA from items on this list there is a more than reasonable chance that all the other items that didn't make the list will make up the other half. Best wishes, -- Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "... and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

- Hide quoted text -- Show quoted text - > If you don't like the idea of supplementation, here is a site I > found after a *very* quick Google for "Best food sources - > magnesium". > http://www.solidrecords.com/Net_Vibes/Food_Connection/Nutrition_Cent > er/Magnesium.html > It's probably as good as any other I'd find. > Almonds or hazelnuts --         2 ounces 170 mg > Spinach, fresh, cooked ---      1 cup    155 mg > Swiss chard, fresh, cooked ---  1 cup    150 mg > Sunflower seeds, dried ---     1/4 cup   130 mg > Halibut or mackerel, cooked --- 4 ounces 120 mg > Tofu ---                        4 ounces 120 mg > Wheat bran ---                1/4 ounces  90 mg > Rice, brown, cooked ---         1 cup     85 mg > Avocado ---                     6 ounces  70 mg > Beans (legumes), cooked ---     1 cup     35 mg > Adult RDA is 400 mg > Magnesium helps reduce the risk of heart disease. It also works with > calcium in forming bones and teeth. > Annette

That canned mackerel is looking better and better. Dirt cheap, tasty, and loaded with good vits and minerals. I make fish cakes at least a couple of times a week. Hubby loves the stuff, despite the fact I keep telling him it's good for him ;-) The secret is the fresh lime juice and grated zest...Top with tomato salsa and it's great! No wonder the grocery store is sold out often. I buy 6-8 cans at a time to make sure there's always some in the house. Vicki

Response:

> The search engine makes it look like there's yet another great reason to eat > sunflower seeds roasted in the shell. They've got lots of magnesium besides > the healthy oils, fiber, AND the ability to make a person feel like they've > eaten something when they haven't. >Just for the fun of it see if you can discover which categories of >food have the most magnesium per 100 gram. >http://yarrow.best.vwh.net/Usda_data/foods.cgi?state_num=5

Note that it's per 100 grams, though.  How many "servings" of each is 100 grams?  It may be that what looks like the "best" is less so when you consider eating 100 grams of each. It's also interesting to note that although the highest concentrations are in this category, three other categories each have _one_ item with high concentrations of magnesium. My father was recently diagnosed diabetic.  He has little experience at reading food labels (grew his own food much of his life) so I wrote for him a "short" (four pages and growing!) overview of nutrition.  One excerpt follows:        Knowingly selecting certain foods (once you know what        they are) can more reliably meet certain needs.  On the        other hand, plenty of opportunists (and misguided fans)        are constantly proclaiming this or that food item as        the "miracle cure" for almost everything.  But faddishly        consuming large amounts of one alleged "miracle food" is        a good way to be deficient in something that food lacks.        If you don't have time for extensive study, one approach        is just to "hedge your bets" by having a wide variety of        foods, especially vegetables of various colors.

Response:

The search engine makes it look like there's yet another great reason to eat sunflower seeds roasted in the shell. They've got lots of magnesium besides the healthy oils, fiber, AND the ability to make a person feel like they've eaten something when they haven't. -- Jenny 168.5/145/145  Achieved Second Goal! 9/1998 - 8/2001 and 11/10/02 - Now http://www.geocities.com/jenny_the_bean/jennypics.htm  Before and After Photos http://www.geocities.com/jenny_the_bean How to calculate your need for protein * How much people really lose each month *  Water Weight Gain & Loss * The "Two Gram Cure" for Hunger Cravings * Characteristics of Successful Dieters * Indispensible Low Carb Treats * Should You Count that Low Impact Carb? * Curing Ketobreath

- Hide quoted text -- Show quoted text -> This post not CC'd by email >> Quentin, >> Thanks for the very helpful analysis! >I'll second that. I really appreciate your posts Quentin, they're >excellent. > G'day G'day David, >  Thank you.  For what it is worth I'm glad I don't have to do it all. > There are some others of like mind who figure people here do deserve > the best of what each of us has to offer. >And for what it's worth, I just had my 3 month checkup today and as a >coincidence my physician asked me to try taking 500mg of magnesium 1x a day >for the next three months. Looks like he's been reading the same research >;-) > Magnesium is tricky stuff to test in the body. The levels can appear > OK when they are not.  The crucial levels are in the red blood cells > RBC, so sometimes the test that is ordered has a name like RBC Mg. > The good news is magnesium isn't being marketed in some patented > complex.  That would make for a whole other set of issues. > Just for the fun of it see if you can discover which categories of > food have the most magnesium per 100 gram. > http://yarrow.best.vwh.net/Usda_data/foods.cgi?state_num=5 > Best wishes, > -- > Quentin Grady       ^  ^  / > New Zealand,       >#,#< [ >                     / / > "... and the blind dog was leading." > http://homepages.paradise.net.nz/quentin

Response:

- Hide quoted text -- Show quoted text - >This post not CC'd by email >Magnesium Supplement Helpful in Diabetes Control >By David Douglas >NEW YORK (Reuters Health) Apr 16 - Oral magnesium supplementation improves >insulin sensitivity and metabolic control in certain type 2 diabetics, >researchers report in the April issue of Diabetes Care. >G'day G'day Jenny, >  Thank you for bringing this Reuters Health article to our attention. . . . .(snip). . .. >OK. >    Who is Dr Martha Rodriguez-Moran?   A quick check of Pubmed shows >she has some thing like 47 abstracts listed, many of them on insulin >sensitivity.  Some of them relate to magnesium serum levels. > How general a conclusion is she reaching? >Well she makes it clear right from the start that she is referring to >CERTAIN T2 diabetics ... not all T2 diabetics. >Best wishes, >-- >Quentin Grady       ^  ^  / >New Zealand,       >#,#< [ >                    / / >"... and the blind dog was leading."

    What I like about the study (besides the fact that she managed to publish in reputable, peer-reviewed journals) is the fact that she went directly to HOMA (a measure of Insulin Resistance) and derived a conclusion based on first principles. . .a direct reduction in Insulin Resistance. So many of these diabetic studies are based on fasting bG or HbA1c.   When you look at them, they really state:     " Some folks who were wildly out of control used our stuff,  and they ended up a bit less out of control. . .so it must be wonderful" She said:     "I measured magnesium levels and Insulin Resistance.    Magnesium levels were low,  Insulin Resistance was high.    I gave them magnesium.   Magnesium levels went up,  Insulin Resistance went down a lot though it was still too high" Good of you to put the time in and pick this thing apart for us. Regards   Old Al

Response:

If you don't like the idea of supplementation, here is a site I found after a *very* quick Google for "Best food sources - magnesium". http://www.solidrecords.com/Net_Vibes/Food_Connection/Nutrition_Cent er/Magnesium.html It's probably as good as any other I'd find. Almonds or hazelnuts --         2 ounces 170 mg Spinach, fresh, cooked ---      1 cup    155 mg Swiss chard, fresh, cooked ---  1 cup    150 mg Sunflower seeds, dried ---     1/4 cup   130 mg Halibut or mackerel, cooked --- 4 ounces 120 mg Tofu ---                        4 ounces 120 mg Wheat bran ---                1/4 ounces  90 mg Rice, brown, cooked ---         1 cup     85 mg Avocado ---                     6 ounces  70 mg Beans (legumes), cooked ---     1 cup     35 mg Adult RDA is 400 mg Magnesium helps reduce the risk of heart disease. It also works with calcium in forming bones and teeth. Annette

Response:

@bob.news.rcn.net: > Quentin, > Thanks for the very helpful analysis!

I'll second that. I really appreciate your posts Quentin, they're excellent. And for what it's worth, I just had my 3 month checkup today and as a coincidence my physician asked me to try taking 500mg of magnesium 1x a day for the next three months. Looks like he's been reading the same research ;-)

Response:

This post not CC'd by email > Quentin, > Thanks for the very helpful analysis! >I'll second that. I really appreciate your posts Quentin, they're >excellent.

G'day G'day David,  Thank you.  For what it is worth I'm glad I don't have to do it all. There are some others of like mind who figure people here do deserve the best of what each of us has to offer. >And for what it's worth, I just had my 3 month checkup today and as a >coincidence my physician asked me to try taking 500mg of magnesium 1x a day >for the next three months. Looks like he's been reading the same research >;-)

Magnesium is tricky stuff to test in the body. The levels can appear OK when they are not.  The crucial levels are in the red blood cells RBC, so sometimes the test that is ordered has a name like RBC Mg.     The good news is magnesium isn't being marketed in some patented complex.  That would make for a whole other set of issues. Just for the fun of it see if you can discover which categories of food have the most magnesium per 100 gram. http://yarrow.best.vwh.net/Usda_data/foods.cgi?state_num=5   Best wishes, -- Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "... and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

Quentin, Thanks for the very helpful analysis! -- Jenny 168.5/145/145  Achieved Second Goal! 9/1998 - 8/2001 and 11/10/02 - Now http://www.geocities.com/jenny_the_bean How to calculate your need for protein * How much people really lose each month *  Water Weight Gain & Loss * The "Two Gram Cure" for Hunger Cravings * Characteristics of Successful Dieters * Indispensible Low Carb Treats * Should You Count that Low Impact Carb? * Curing Ketobreath

- Hide quoted text -- Show quoted text -> This post not CC'd by email >Magnesium Supplement Helpful in Diabetes Control >By David Douglas >NEW YORK (Reuters Health) Apr 16 - Oral magnesium supplementation improves >insulin sensitivity and metabolic control in certain type 2 diabetics, >researchers report in the April issue of Diabetes Care. > G'day G'day Jenny, >   Thank you for bringing this Reuters Health article to our attention. > In many people's minds Reuters provides a more impartial news service > than some. A few weeks ago there was an upsurge of people using the > internet to visit Reuters to get less biased news.  So basically, > thank you for bringing us this article to a forum where the aspects > relevant to us can be rationally discussed.  If such matters can't be > rationally discussed then what will happen IMHO is that the number of > people who uncritically believe every newspaper report will increase > even if we are unaware of them.  For the moment I have an open mind as > to whether or not there is any conclusion to be drawn about magnesium > and T2 diabetes. > OK. >     Who is Dr Martha Rodriguez-Moran?   A quick check of Pubmed shows > she has some thing like 47 abstracts listed, many of them on insulin > sensitivity.  Some of them relate to magnesium serum levels. >  How general a conclusion is she reaching? > Well she makes it clear right from the start that she is referring to > CERTAIN T2 diabetics ... not all T2 diabetics. >Drs. Martha Rodriguez-Moran and Fernando Guerrero-Romero of the Mexican >Social Security Institute, Durango, note that hypomagnesemia is frequently >found in diabetes and "could be involved in the development of poor >metabolic control and chronic complications." However, randomized, >controlled studies on this subject, they add, are "scare and controversial." >Overall, Dr. Rodriguez-Moran, told Reuters Health, it is unfortunate that >the "magnesium ion is a typically overlooked electrolyte." >To further investigate whether oral magnesium supplementation might be >helpful in type 2 diabetics with decreased serum magnesium levels, the >researchers conducted a double-blind trial involving 63 such subjects. >They were randomized to receive a daily treatment with a solution containing >2.5 g of magnesium chloride or to placebo. >At the end of the 16-week treatment period, compared to the placebo group, >those who received the supplement had significantly higher serum magnesium >concentration (0.74 versus 0.65 nmol/L) and lower values (3.8 versus 5.0) >for the homeostasis model assessment for insulin resistance index (HOMA-IR). >There was also a reduction in glycosylated hemoglobin (HbA1c) levels (8.0 >versus 10.1%). > Here we find something very significant. > These T2s in the study were way out of control. High levels of blood > glucose give the kidneys more than the usual workout.  My first > reaction was to dismiss the research as irrelevant to diabetics in > good control and to think, "Well the real answer for those who aren't > is to get their bg down." >These results, Dr Rodriguez-Moran continued, "show the indubitable benefits >of oral magnesium supplementation as an adjuvant therapy for reducing >fasting glucose, HbA1c, and HOMA-IR index in subjects with type 2 diabetes. >" > That conclusion seems more general than a single research project > would show.  Heck "indubitable" is pretty strong language for a > scientist. >Taking into account the low cost and safety of magnesium supplementation, >she concluded, it appears that "oral magnesium could be a useful therapeutic >tool for achieving metabolic control in subjects with diabetes." >Diabetes Care 2003;26:1147-1152. > So I dug out one of her papers on Metabolic Syndrome.  People with > metabolic syndrome aren't YET experiencing high levels of blood > glucose.  They sure as heck don't have A1c of 10 or even 8. > Most of them have A1c that we'd be delighted to have. > The point is, if low serum magnesium is evident in people with > metabolic syndrome AND out of control T2s then the range of people for > whom it is applicable is much wider than one might expect from reading > an abstract of a single bit of research. > 1: Acta Diabetol  2002 Dec;39(4):209-13 > Low serum magnesium levels and metabolic syndrome. > Guerrero-Romero F, Rodriguez-Moran M. > Research Group on Diabetes and Chronic Illnesses, Medical Research > Unit in Clinical Epidemiology, Mexican Social Security Institute, > Durango, Mexico. > Low serum magnesium levels are related to diabetes mellitus (DM) and > high blood pressure (HBP), but as far as we know, there are no > previous reports that analyzed the serum magnesium concentration in > individuals with metabolic syndrome (MS). > We performed a cross-sectional population-based study to compare 192 > individuals with MS and 384 disorder-free control subjects, matched by > age and gender. Magnesium supplementation treatment and conditions > likely to provoke hypomagnesemia, including previous diagnosis of > diabetes mellitus (DM) and/or high blood pressure (HBP), were > exclusion criteria. In this regard, only incident cases of DM and HBP > were included. > MS was defined by the presence at least of two of the following > features: hyperglycemia (>/=7.0 mmol/l); HBP (>/=160/90 mmHg); > dyslipidemia (fasting triglycerides >/=1.7 mmol/l and/or > HDLcholesterol <1.0 mmol/l); and obesity (body mass index >/=30 > kg/m(2) and/or waist-to-hip ratio >/=0.85 in women or >/=0.9 in men). > Low serum magnesium levels were identified in 126 (65.6%) and 19 > (4.9%) individuals with and without MS, p<0.00001. The mean serum > magnesium level among subjects with MS was 1.8+/-0.3 mg/dl, and among > control subjects 2.2+/-0.2 mg/dl, p<0.00001. > There was a strong independent relationship between low serum > magnesium levels and MS (odds ratio (OR)=6.8, CI(95%) 4.2-10.9). > Among the components of MS, dyslipidemia (OR 2.8, CI(95%) 1.3-2.9) and > HBP (OR 1.9, CI(95%) 1.4-2.8) were strongly related to low serum > magnesium levels. > This study reveals a strong relationship between decreased serum > magnesium and MS. > PMID: 12486495 [PubMed - in process] > Best wishes, > — > Quentin Grady       ^  ^  / > New Zealand,       >#,#< [ >                     / / > "... and the blind dog was leading." > http://homepages.paradise.net.nz/quentin

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cc'd by email This is JUST as worthles now as the LAST idiot who posted it In case you didn't bother to read the last thread.  The study is extremely questionable, too short, too few people.  BUT, the one thing which makes it totally worthless is the fact that they were only dealing with people so out of control that they were dehydrating  (A1c of over 10 !!!) and of COURSE people who are dehydrated need magnesium supplements, ANd potassium, AND ...... > Magnesium Supplement Helpful in Diabetes Control

<crap sniped>

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Ted, Magnesium supplementation helped bring my blood pressure back into control when it was still high on medication. So I'm a big fan.  It isn't expensive and it doesn't seem to hurt people to take it. Worth a try, I'd say. -- Jenny 168.5/145/145  Achieved Second Goal! 9/1998 - 8/2001 and 11/10/02 - Now http://www.geocities.com/jenny_the_bean How to calculate your need for protein * How much people really lose each month *  Water Weight Gain & Loss * The "Two Gram Cure" for Hunger Cravings * Characteristics of Successful Dieters * Indispensible Low Carb Treats * Should You Count that Low Impact Carb? * Curing Ketobreath

- Hide quoted text -- Show quoted text -> cc'd by email > This is JUST as worthles now as the LAST idiot who posted it > In case you didn't bother to read the last thread.  The study is > extremely questionable, too short, too few people.  BUT, the one thing > which makes it totally worthless is the fact that they were only dealing > with people so out of control that they were dehydrating  (A1c of over > 10 !!!) and of COURSE people who are dehydrated need magnesium > supplements, ANd potassium, AND ...... > Magnesium Supplement Helpful in Diabetes Control > <crap sniped>

Response:

This post not CC'd by email >Magnesium Supplement Helpful in Diabetes Control >By David Douglas >NEW YORK (Reuters Health) Apr 16 - Oral magnesium supplementation improves >insulin sensitivity and metabolic control in certain type 2 diabetics, >researchers report in the April issue of Diabetes Care.

G'day G'day Jenny,   Thank you for bringing this Reuters Health article to our attention. In many people's minds Reuters provides a more impartial news service than some. A few weeks ago there was an upsurge of people using the internet to visit Reuters to get less biased news.  So basically, thank you for bringing us this article to a forum where the aspects relevant to us can be rationally discussed.  If such matters can't be rationally discussed then what will happen IMHO is that the number of people who uncritically believe every newspaper report will increase even if we are unaware of them.  For the moment I have an open mind as to whether or not there is any conclusion to be drawn about magnesium and T2 diabetes. OK.     Who is Dr Martha Rodriguez-Moran?   A quick check of Pubmed shows she has some thing like 47 abstracts listed, many of them on insulin sensitivity.  Some of them relate to magnesium serum levels.  How general a conclusion is she reaching?   Well she makes it clear right from the start that she is referring to CERTAIN T2 diabetics ... not all T2 diabetics. - Hide quoted text -- Show quoted text ->Drs. Martha Rodriguez-Moran and Fernando Guerrero-Romero of the Mexican >Social Security Institute, Durango, note that hypomagnesemia is frequently >found in diabetes and "could be involved in the development of poor >metabolic control and chronic complications." However, randomized, >controlled studies on this subject, they add, are "scare and controversial." >Overall, Dr. Rodriguez-Moran, told Reuters Health, it is unfortunate that >the "magnesium ion is a typically overlooked electrolyte." >To further investigate whether oral magnesium supplementation might be >helpful in type 2 diabetics with decreased serum magnesium levels, the >researchers conducted a double-blind trial involving 63 such subjects. >They were randomized to receive a daily treatment with a solution containing >2.5 g of magnesium chloride or to placebo. >At the end of the 16-week treatment period, compared to the placebo group, >those who received the supplement had significantly higher serum magnesium >concentration (0.74 versus 0.65 nmol/L) and lower values (3.8 versus 5.0) >for the homeostasis model assessment for insulin resistance index (HOMA-IR). >There was also a reduction in glycosylated hemoglobin (HbA1c) levels (8.0 >versus 10.1%).

Here we find something very significant.   These T2s in the study were way out of control. High levels of blood glucose give the kidneys more than the usual workout.  My first reaction was to dismiss the research as irrelevant to diabetics in good control and to think, "Well the real answer for those who aren't is to get their bg down."   >These results, Dr Rodriguez-Moran continued, "show the indubitable benefits >of oral magnesium supplementation as an adjuvant therapy for reducing >fasting glucose, HbA1c, and HOMA-IR index in subjects with type 2 diabetes. >"

That conclusion seems more general than a single research project would show.  Heck "indubitable" is pretty strong language for a scientist. >Taking into account the low cost and safety of magnesium supplementation, >she concluded, it appears that "oral magnesium could be a useful therapeutic >tool for achieving metabolic control in subjects with diabetes." >Diabetes Care 2003;26:1147-1152.

So I dug out one of her papers on Metabolic Syndrome.  People with metabolic syndrome aren't YET experiencing high levels of blood glucose.  They sure as heck don't have A1c of 10 or even 8.   Most of them have A1c that we'd be delighted to have.   The point is, if low serum magnesium is evident in people with metabolic syndrome AND out of control T2s then the range of people for whom it is applicable is much wider than one might expect from reading an abstract of a single bit of research. 1: Acta Diabetol  2002 Dec;39(4):209-13   Low serum magnesium levels and metabolic syndrome.   Guerrero-Romero F, Rodriguez-Moran M.   Research Group on Diabetes and Chronic Illnesses, Medical Research Unit in Clinical Epidemiology, Mexican Social Security Institute, Durango, Mexico.   Low serum magnesium levels are related to diabetes mellitus (DM) and high blood pressure (HBP), but as far as we know, there are no previous reports that analyzed the serum magnesium concentration in individuals with metabolic syndrome (MS). We performed a cross-sectional population-based study to compare 192 individuals with MS and 384 disorder-free control subjects, matched by age and gender. Magnesium supplementation treatment and conditions likely to provoke hypomagnesemia, including previous diagnosis of diabetes mellitus (DM) and/or high blood pressure (HBP), were exclusion criteria. In this regard, only incident cases of DM and HBP were included. MS was defined by the presence at least of two of the following features: hyperglycemia (>/=7.0 mmol/l); HBP (>/=160/90 mmHg); dyslipidemia (fasting triglycerides >/=1.7 mmol/l and/or HDLcholesterol <1.0 mmol/l); and obesity (body mass index >/=30 kg/m(2) and/or waist-to-hip ratio >/=0.85 in women or >/=0.9 in men). Low serum magnesium levels were identified in 126 (65.6%) and 19 (4.9%) individuals with and without MS, p<0.00001. The mean serum magnesium level among subjects with MS was 1.8+/-0.3 mg/dl, and among control subjects 2.2+/-0.2 mg/dl, p<0.00001. There was a strong independent relationship between low serum magnesium levels and MS (odds ratio (OR)=6.8, CI(95%) 4.2-10.9). Among the components of MS, dyslipidemia (OR 2.8, CI(95%) 1.3-2.9) and HBP (OR 1.9, CI(95%) 1.4-2.8) were strongly related to low serum magnesium levels. This study reveals a strong relationship between decreased serum magnesium and MS.   PMID: 12486495 [PubMed - in process]   Best wishes, — Quentin Grady       ^  ^  / New Zealand,       >#,#< [                     / /     "… and the blind dog was leading." http://homepages.paradise.net.nz/quentin

Response:

Magnesium Supplement Helpful in Diabetes Control By David Douglas NEW YORK (Reuters Health) Apr 16 – Oral magnesium supplementation improves insulin sensitivity and metabolic control in certain type 2 diabetics, researchers report in the April issue of Diabetes Care. Drs. Martha Rodriguez-Moran and Fernando Guerrero-Romero of the Mexican Social Security Institute, Durango, note that hypomagnesemia is frequently found in diabetes and "could be involved in the development of poor metabolic control and chronic complications." However, randomized, controlled studies on this subject, they add, are "scare and controversial." Overall, Dr. Rodriguez-Moran, told Reuters Health, it is unfortunate that the "magnesium ion is a typically overlooked electrolyte." To further investigate whether oral magnesium supplementation might be helpful in type 2 diabetics with decreased serum magnesium levels, the researchers conducted a double-blind trial involving 63 such subjects. They were randomized to receive a daily treatment with a solution containing 2.5 g of magnesium chloride or to placebo. At the end of the 16-week treatment period, compared to the placebo group, those who received the supplement had significantly higher serum magnesium concentration (0.74 versus 0.65 nmol/L) and lower values (3.8 versus 5.0) for the homeostasis model assessment for insulin resistance index (HOMA-IR). There was also a reduction in glycosylated hemoglobin (HbA1c) levels (8.0 versus 10.1%). These results, Dr Rodriguez-Moran continued, "show the indubitable benefits of oral magnesium supplementation as an adjuvant therapy for reducing fasting glucose, HbA1c, and HOMA-IR index in subjects with type 2 diabetes. " Taking into account the low cost and safety of magnesium supplementation, she concluded, it appears that "oral magnesium could be a useful therapeutic tool for achieving metabolic control in subjects with diabetes." Diabetes Care 2003;26:1147-1152. — Jenny 168.5/145/145  Achieved Second Goal! 9/1998 – 8/2001 and 11/10/02 – Now http://www.geocities.com/jenny_the_bean How to calculate your need for protein * How much people really lose each month *  Water Weight Gain & Loss * The "Two Gram Cure" for Hunger Cravings * Characteristics of Successful Dieters * Indispensible Low Carb Treats * Should You Count that Low Impact Carb? * Curing Ketobreath

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